Milk peptides and blood pressure.
نویسندگان
چکیده
Epidemiological studies suggest that milk consumption and dietary intake of dairy proteins are inversely related to the risk for hypertension. Also, some intervention studies have shown a blood pressure-lowering effect of milk products and dairy proteins. Milk peptides are formed from milk proteins by enzymatic breakdown by digestive enzymes or by the proteinases formed by lactobacilli during the fermentation of milk. Several milk peptides have been shown to have antihypertensive effects in animal and in clinical studies. The most studied mechanism underlying the antihypertensive effects of milk peptides is inhibition of angiotensin-converting enzyme. Milk peptides may also have other additional mechanisms to lower blood pressure such as opioid-like activities and mineral-binding and antithrombotic properties. The future challenge is to identify the antihypertensive components in milk and their mechanisms of action and thus to find more possibilities for using these constituents and products as a dietary treatment of hypertension.
منابع مشابه
The Journal of Nutrition Effects of Probiotics and Prebiotics Milk Peptides and Blood Pressure
Epidemiological studies suggest that milk consumption and dietary intake of dairy proteins are inversely related to the risk for hypertension. Also, some intervention studies have shown a blood pressure-lowering effect of milk products and dairy proteins. Milk peptides are formed from milk proteins by enzymatic breakdown by digestive enzymes or by the proteinases formed by lactobacilli during t...
متن کاملThe Emerging Role of Dairy Proteins and Bioactive Peptides in Nutrition and Health Hypotensive Peptides from Milk Proteins
Hypertension is the major controllable risk factor associated with cardiovascular disease (CVD) events such as myocardial infarction, stroke, heart failure, and end-stage diabetes. A 5 mm Hg decrease in blood pressure has been equated with 16% decrease in CVD. In the U.S. alone current annual antihypertensive drug costs are approximately $15 billion. The renin-angiotensin-aldosterone system is ...
متن کاملAntimicrobial Peptides Derived from Milk: A Review
Milk proteins provide a natural source of bioactive peptides with potential health benefits and applications in the food industry. The release of these peptides from milk proteins is achieved either by hydrolysis using digestive proteases or by lactic acid bacteria fermentation. Peptides, particularly those derived from milk proteins, can exert a wide range of nutritional, functional and biolog...
متن کاملAntihypertensive Peptides from Milk Proteins
Dietary proteins possess a wide range of nutritional and functional properties. They are used as a source of energy and amino acids, which are needed for growth and development. Many dietary proteins, especially milk proteins, contain physiologically active peptides encrypted in the protein sequence. These peptides may be released during gastrointestinal digestion or food processing and once li...
متن کاملFermented milk derives bioactive peptides with antihypertensive effects
Functional foods present great promise for future developments in human nutrition. In the fermented dairy products, milk proteins serve as an important source of a range of bioactive peptides encrypted within the sequence of the native proteins and thus be released by proteolysis. From the bioactive peptides detected in dairy products, is inhibitors of angiotensin I-converting enzyme (ACE), whi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Journal of nutrition
دوره 137 3 Suppl 2 شماره
صفحات -
تاریخ انتشار 2007